简介:  目录:  封面正文 内容介绍：科技百科类杂志，喜欢探索未知的朋友值得阅读。When devastating natural disasters strike, sending in human search and rescue teams can result in even more casualties, as falling debris and unsteady terrain make the area incredibly unsafe. To overcome this, engineers all over the world are developing teams of robots that can assist human first responders or even go it alone. Creating a machine that can overcome all of the obstacles of a disaster zone isn’t easy though, as they will have to be able to move rubble, avoid hazards and break through walls, not to mention tackle stairs and open doors. In Issue 82 of How It Works discover all of the challenges rescue robots will have to face, and meet the ‘bots that are already prepared to come to our rescue.Also in this issue:The 10 most dangerous job in the world, and how science and tech are making them saferCamera tech: Exposing the inner workings of your digital cameraAmazon – from click to delivery: Take a look inside the online retailer’s warehousesExtreme truckers: Discover how man and machine conquer the deadliest roads on Earth内容截图：...

第1章 初识Access 2010 11.1 走进Access 2010 11.2 Access 2010的新特点 11.3 Access 2010的操作环境 41.4 “文件”选项卡 111.5 个性化设置 131.6 善用帮助 16动手实验 18第2章 数据库的创建和操作 192.1 认识数据库 192.2 数据库应用系统开发 202.3 数据库应用系统开发方法 212.4 数据库的创建 242.5 组织数据库对象 272.6 操作数据库对象 28动手实验 31第3章 表 323.1 表的设计 323.2 创建表 343.3 在表中添加和删除字段 413.4 创建查阅字段列 423.5 字段属性 463.6 定义数据表的关系 513.7 创建和使用附件字段 543.8 在Access中使用运算符和表达式 56动手实验 61第4章 操作和修饰表 634.1 数据表的操作 634.2 数据检索 664.3 设置数据表的格式 714.4 对数据表中的行汇总统计 744.5 Access数据表的导出 75动手实验 79第5章 选择查询 815.1 查询 815.2 使用向导创建选择查询 825.3 使用查询设计视图 845.4 编辑和修改查询 915.5 参数查询 945.6 使用查询执行计算 965.7 创建交查表查询 1005.8 创建查找重复项查询 1045.9 使用向导“查找表之间 不匹配项的记录” 1065.10 操作查询 107动手实验 112第6章 窗体 1136.1 认识窗体 1136.2 窗体的创建 1166.3 窗体的设计视图 1236.4 理解和使用属性 1276.5 窗体中控件及其应用 1296.6 创建选项卡窗体 1426.7 窗体的布局和格式调整 1516.8 美化窗体 1546.8 综合应用 157动手实验 161第7章 报表 1627.1 认识Access报表 1627.2 报表的创建 1647.3 使用“设计视图”创建报表 1687.4 报表的计算 1737.5 报表的高级应用 1787.6 报表的预览和打印 182动手实验 183第8章 宏 1848.1 了解宏 1848.2 宏的结构 1868.3 宏选项卡和设计器 1868.4 创建宏 1898.5 创建嵌入宏 1928.6 宏的运行和调试 1978.7 典型的宏操作分析 199动手实验 200第9章 在导航窗格中组织项目 2019.1 了解导航窗格 2019.2 导航窗格的功能和结构 2019.3 导航窗格对对象的管理 2029.4 使用导航窗格管理数据库对象 2039.5 创建自定义类别和组 207动手实验 210第10章 数据库管理 21110.1 Access安全性的新增功能 21110.2 设置数据库密码 21410.3 压缩和修复数据库 21510.4 备份和恢复数据库 21610.5 生成ACCDE文件 218动手实验 220第11章 系统集成 22111.1 创建应用系统管理窗体 22111.2 设置数据库启动选项 22911.3 生成ACCDE文件 232小结232 动手实验：教学管理系统设计 232 内容简介:Access 2010是微软公司推出的最新版本,与其他版本相比，Access 2010除了继承和发扬了以前版本的功能强大、界面友好、易学易用的优点之外，在界面的易用性方面和支持网络数据库方面进行了很大改进。本书共分为11章。全书由浅入深地对Access 2010进行了详细的讲解，并以示例为引导介绍Access的各项功能，尤其是它的新功能，同时每个示例都配有许多图片。本书注重实践，只要按照示例一步一步去做就可以掌握Access的基本内容和常用功能，完成一个基本的数据库开发工作。学习网www.minxue.net下载地址分流下载: [Access2010中文版入门与实例教程].张强等.扫描版.pdf内容截图: ...

简介:  目录:  导言为什么要学习数学为什么学好数学会让人变得更有智慧数学概论只有天才才能成为数学家吗为什么各个国家中小学都开设数学课为什么数学的结论是可靠的为什么数学是有用的为什么数学建模越来越受重视为什么数学已成为一种关键的技术数与运算为什么全世界通用阿拉伯数字 10为什么0的发明是对世界文明的杰出贡献 12符号+、一、x、+、=是怎么来的 12为什么计算机要使用二进制 14为什么说中国人最早提出了二进制的思想计时为什么用六十进制为什么数学中要用很多符号小数点是怎么来的 16为什么要规定先乘除后加减 18为什么分数相加要先通分为什么在乘除运算中规定负负得正 2C为什么规定a^0=l 20A*B是否一定等于B*A 22为什么小数相加要对齐小数点而小数相乘不用对齐…24... 内容介绍：最正宗的《十万个为什么》——少年儿童出版社出版，本版为最新第六版。最权威的编撰阵容！——中科协韩启德院士任总编，21位中国科学院和中国工程院院士等顶级科学家担任分册主编，110余位两院院士组成的编委会！全书共600万字，7000余幅彩色图片，收入4500个代表科技发展前沿和青少年关心的热点问题。 本套丛书共分三大板块共18个分册：（1）基础板块：数学、物理、化学、天文、地 球、生命；（2）专题板块：动物、植物、古生物、医学、建筑与交通、电子与信息；（3）热点板块：大脑与认知、海洋、能源与环境、武器与国防、航天与航 空、灾难与防护。 本册为数学分册。数学是人类知识精华的具体体现，它影响着人类活动的每一个领域。该分册通过一个个有趣的问题，深入浅出地介绍生活中与数学和数字相关的现象和知识，强调数学中有趣、好玩的内容。序言　　韩启德　　全国政协副主席　　中国科学技术协会主席　　病理生理学家、中国科学院院士、发展中国家科学院院士　　　　经过数百位编委、作者和编辑历时三年的辛勤努力，第六版《十万个为什么》终于与广大读者见面了。对于中国的科技界、教育界和出版界，以及千千万万的少年儿童来说，这都是值得高兴的一件事。　　《十万个为什么》是由少年儿童出版社于1961年出版的一套科普图书。在半个世纪的岁月里，这套书先后出版了五个版本，累计发行量超过1亿册，是新中国几代青少年的启蒙读物，在弘扬科学精神、传播科学知识、提高全民科学素质方面发挥了巨大作用。在我国，至今还没有一套科普读物能像《十万个为什么》那样经得起如此长时间的检验，并产生如此巨大的社会影响。　　进入21世纪以来，科学技术的发展日新月异，尤其在网络通信、低碳环保、基因工程、航空航天、新能源、新材料等领域，研究进展更是一日千里，乃至从根本上改变着人们的生活与工作方式。为适应科技发展带来的深刻社会变革，提高国家的综合国力和竞争力，党和政府高度重视加强科学技术普及，重视提高全民科学素质，并将国家科普能力建设作为建设创新型国家的一项基础性、战略性任务，这对我国的科普出版提出了更高的目标。　　2006年,国务院正式颁布实施《全民科学素质行动计划纲要》，其中特别强调要提升未成年人的科学素养，因为只有从青少年时期就开始养成科学的思维方式与行为习惯，将创新精神与实践能力并重，才能最终使得全民的科学素质得到根本性的提高。为此，编辑出版一套崭新的适应时代发展要求的《十万个为什么》，使其在繁荣我国科普创作的进程中发挥“旗帜”作用，其意义是非常深远的。好奇心是青少年的可贵特质，是驱使他们亲近和接受科学的动力，一定要保护好。从50年来的经验看，“一问一答”是个好形式，也是《十万个为什么》被大家喜爱的重要原因，在编纂第六版《十万个为什么》时我们坚持了这一好形式，并力争在传授科学知识的同时，引导读者去思索问题，去感受科学文化和科学精神，去体会科学探索的乐趣。　　出于积极参与科学普及工作，提高全民科学素质的社会责任感，中国科学院和中国工程院共有百余位院士应邀担任了第六版《十万个为什么》的编委。其中20余位院士在百忙之中担任了各分册的主编，具体负责组织相关分册的编纂工作，有40余位院士亲自撰稿。此外，还有700余位来自世界各地、各个学科的优秀科学家和科普作家参与了新版《十万个为什么》的编写。这么多高层次科学家参与到一套科普图书的编纂工作中来，这在我国科普出版史上是空前的。阵容强大的编委会和作者队伍，为新版《十万个为什么》的科学性、前沿性、权威性和可读性提供了最可靠的保证。在此，我也谨向所有参与第六版《十万个为什么》编纂工作的编委、主编、作者和社会各界表示衷心的感谢和深深的敬意。　　第六版《十万个为什么》在总结前五版成功经验，并广泛征求各方面意见的基础上，综合考虑时代的发展和青少年读者的实际需要，将全书分为三大板块共18个分册。基础板块包括数学、物理、化学、天文、地球、生命，是传统六大基础学科；专题板块包括动物、植物、古生物、医学、建筑与交通、电子与信息，是由基础学科衍生出来的重点传统学科；热点板块包括大脑与认知、海洋、能源与环境、航空与航天、武器与国防、灾难与防护，则是近些年发展特别迅速，引起社会广泛关注的热点领域。在编纂每一分册的过程中，我们根据这个学科或专题的内容，充分考虑知识体系的完整性和科学发展的前瞻性，问题的设计和分布尽量与学科或专题的内在结构相吻合，从而使每一分册都成为具有完整的内在知识体系的读物。现代科学技术发展的一大特点是学科之间的交叉融合，相信小读者们在阅读过程中也会在不同的分册中发现一些共性的问题。　　第六版《十万个为什么》在形式上适应了当代青少年的阅读需求，与国际上同类图书的最新出版潮流相接轨，首次推出彩色图文版，用大量彩色图片向读者展示当代科技前沿的无穷魅力。内容上具有鲜明的时代特色，从基础、前沿、关键、战略四个方面来组织问题和编写稿件，重点关注科技发展的前沿和当代青少年关心的热点问题。尤其值得称道的是，书中的大量“为什么”是通过各种形式向全国少年儿童征集来的，力求将当前孩子们最关心、最爱问的问题介绍给他们。同时，新版《十万个为什么》更加注重思考过程，提倡科学精神，引导创造探索，关注科学与人文、科学与社会的关系，通过“微问题”“微博士”“实验场”“科学人”“关键词”等小栏目激发青少年的好奇心和探究心理。　　我们相信，第六版《十万个为什么》将以全新的问题、全新的体系、全新的内容、全新的样式，以及数字化时代全新的技术手段，再现《十万个为什么》每一版都曾有的辉煌，掀起中国科普出版和科学普及的又一个新高潮。第六版《十万个为什么》的出版，必将引领更多青少年走向科学，使共和国涌现出更多的栋梁之材。同时，这套书的出版，对于贯彻落实《全民科学素质行动计划纲要》精神，促使当代中国广大青少年科学世界观的形成和科学创新能力的提高，推进全社会在讲科学、爱科学、用科学上形成更加浓厚的氛围，使全民科学素质再上新台阶，发挥不可替代的关键作用。内容截图：==提供下载：链接：http://pan.baidu.com/s/1qXl1mMg 密码：bg2b ...

简介:  目录:  About the authorsA Note on the Nature of SciencePreface1. The Foundations of Biochemistry1.1. Cellular Foundations1.2. Chemical Foundations1.3. Physical Foundations1.4. Genetic Foundations1.5. Evolutionary FoundationsI. STRUCTURE AND CATALYSIS2. Water2.1. Weak Interactions in Aqueous Solution2.2. Ionization of Water, Weak Acids, and Weak Bases2.3. Buffering against pH Changes in Biological systems2.4. Water as a Reactant2.5. The Fitness of the Aqueous Environment for Living Organisms3. Amino Acids, Peptides and Proteins3.1. Amino Acids3.2. Peptides and Proteins3.3. Working with Proteins3.4. The Structure of Proteins: Primary Structure4. The Three-Dimensional Structure of Proteins4.1. Overview of Protein Structure4.2. Protein Secondary Structure4.3. Protein Tertiary and Quaternary Structures4.4. Protein Denaturation and Folding5. Protein Function5.1. Reversible Binding of a Protein to a Ligand: Oxygen-Binding Proteins5.2. Complementary Interactions between Proteins and Ligands: The Immune System and Immunoglobulins5.3. Protein Interactions Modulated by Chemical Energy: Actin, Myosin, and Molecular Motors6. Enzymes6.1. An Introduction to Enzymes6.2. How Enzymes Work6.3. Enzyme Kinetics as an Approach to Understanding Mechanism6.4. Examples of Enzymatic Reactions6.5. Regulatory Enzymes7. Garbohydrates and Glycobiology7.1. Monosaccharides and Disaccharides7.2. Polysaccharides7.3. Glycoconjugates: Proteoglycans, Glycoproteins and Glycolipids7.4. Carbohydrates as Informational Molecules: The Sugar Code7.5. Working with Carbohydrates8. Nucleotides and Nucleic Acids8.1. Some Basics8.2. Nucleic Acid Structure8.3. Nucleic Acid Chemistry8.4. Other Functions of Nucleotides9. DNA-Based Information Technologies9.1. DNA Clonning: The Basics9.2. From Genes to Genomes9.3. From Genomes to Proteomes9.4. Genome Alterations and New Products of Biotechnology10. Lipids10.1. Storage Lipids10.2. Structural Lipids in Membranes10.3. Lipids as Signals, Cofactors, and Pigments10.4. Working with Lipids11. Biological Membranes and Transport11.1. The Composition and Architecture of Membranes11.2. Membrane Dynamics11.3. Solute Transport across Membranes12. Biosignaling12.1. General Features of Signal Transduction12.2. G Protein-Coupled Receptors and Second Messengers12.3. Receptor Tyrosine Kinases12.4. Receptor Guanylyl Cyclases, cGMP, and Protein Kinase G12.5. Multivalent Adaptor Proteins and Membrane Raffts12.6. Gated Ion Channels12.7. Integrins: Bidirectional Cell Adhesion Receptors12.8. Regulation of Transcription by Steroid Hormones12.9. Signaling in Microorganisms and Plants12.10. Sensory Transduction in Vision, Olfaction, and Gustation12.11. Regulation of the Cell Cycle by Protein Kinases12.12. Oncogenes, Tumor Supressor Genes, and Programmed Cell DeathII BIOENERGETICS AND METABOLISM13. Bioenergetics and Biochemical Reaction Types13.1. Bioenergetics and Thermodynamics13.2. Chemical Logic and Common Biochemical Reactions13.3. Phosphoryl Group Transfer and ATP13.4. Biological Oxidation-Reduction Reactions14. Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway14.1. Glycolysis14.2. Feeder Pathways for Glycolysis14.3. Fates of Pyruvate under Anaerobic Conditions: Fermentation14.4. Glugoneogenesis14.5. Pentose Phosphate Pathway of Glucose Oxidation15. Principles of Metabolic Regulation15.1. Regulation of Metabolic Pathways15.2. Analysis of Metabolic Control15.3. Coordinated Regulation of Glycolysis and Gluconeogenesis15.4. The Metabolism of Glycogen in Animals15.5. Coordinated Regulation of Glycogen Synthesis and Breakdown16. The Citric Acid Cycle16.1. Production of Acetyl-CoA (Activated Acetate)16.2. Reactions of the Citric Acid Cycle16.3. Regulation of the Citric Acid Cycle16.4. The Glyoxylate Cycle17. Fatty Acid Catabolism17.1. Digestion, Mobilization, and Transport of Fats17.2. Oxidation of Fatty Acids17.3. Ketone Bodies18. Amino Acid Oxidation and the Production of Urea18.1. Metabolic Fates of Amino Groups18.2. Nitrogen Excretion and the Urea Cycle18.3. Pathways of Amino Acid Degradation19. Oxidative Phosphorylation and PhotophosphorylationOXIDATIVE PHOSPHORYLATION19.1. Electron-Transfer Reactions in Mitochondria19.2. ATP Synthesis19.3. Regulation of Oxidative Phosphorylation19.4. Mitochondria in Thermogenesis, Steroid Synthesis, and Apoptosis19.5. Mitochondrial Genes: Their Origin and the Effects of MutationsPHOTOSYNTHESIS: HARVESTING LIGHT ENERGY19.6. General Features of Photophosphorylation19.7. Light Absorption19.8. The Central Photochemical Event: Light-Driven Electron Flow19.9. ATP Synthesis by Photophosphorylation19.10. The Evolution of Oxygenic Photosynthesis20. Carbohydrate Biosynthesis in Plants and Bacteria20.1. Photosynthetic Carbohydrate Synthesis20.2. Photorespiration and the C4 and CAM Pathways20.3. Biosynthesis of Starch and Sucrose20.4. Synthesis of Cell Wall Polysaccharides: Plant Cellulose and Bacterial Peptidoglycan20.5. Integration of Carbohydrate Metabolism in the Plant Cell21. Lipid Biosynthesis21.1. Biosynthesis of Fatty Acids and Eicosanoids21.2. Biosynthesis of Triacylglycerols21.3. Biosynthesis of Membrane Phospholipids21.4. Biosynthesis of Cholesterol, Steroids, and Isoprenoids22. Biosynthesis of Amino Acids, Nucleotides, and Related Molecules22.1. Overview of Nitrogen Metabolism22.2. Biosynthesis of Amino Acids22.3. Molecules Derived from Amino Acids22.4. Biosynthesis and Degradation of Nucleotides23. Hormonal Regulation and Integration of Mammalian Metabolism23.1. Hormones: Diverse Structures for Diverse Functions23.2. Tissue-Specific Metabolism: The Division of Labour23.3. Hormonal Regulation of Fuel Metabolism23.4. Obesity and the Regulation of Body Mass23.5. Obesity, the Metabolic Syndrome, and Type 2 DiabetesIII INFORMATIVE PATHWAYS24. Genes and Chromosomes24.1. Chromosomal Elements24.2. DNA Supercoiling24.3. The Structure of Chromosomes25. DNA Metabolism25.1. DNA Replication25.2. DNA Repair25.3. DNA Recombination26. RNA Metabolism26.1. DNA-Dependent Synthesis of RNA26.2. RNA Processing26.3. RNA-Dependent Synthesis of RNA and DNA27. Protein Metabolism27.1. The Genetic Code27.2. Protein Synthesis27.3. Protein Targeting and Degradation28. Regulation of Gene Expression28.1. Principles of Gene Regulation28.2. Regulation of Gene Expression in Bacteria28.3. Regulation of Gene Expression in EukaryotesAppendix A. Common Abbreviations in the Biochemical Research Literature [A-4]Appendix B. Abbreviated Solutions to Problems [AS-35]Glossary [G-17]Credits [C-8]Index [I-41]Boxes [given here in toto only for sake of clarity; first number indicates the actual chapter]Box 1-1 Molecular Weight, Molecular Mass, and Their Correct UnitsBox 1-2 Louis Pasteur and Optical Activity: In Vino, VeritasBox 1-3 Entropy: The Advantages of Being DisorganizedBox 2-1 Medicine: On Being One's Own Rabbit (Don't Try This at Home!)Box 3-1 Methods: Absorption of Light by Molecules: The Lambert-Beer LawBox 3-2 Methods: Investigating Proteins with Mass SpectrometryBox 3-3 Consensus Sequences and Sequence LogosBox 4-1 Methods: Knowing the Right Hand from the LeftBox 4-2 Permanent Waving is Biochemical EngineeringBox 4-3 Medicine: Why Sailors, Explorers, and College Students Should Eat Their Fresh Fruits and VegetablesBox 4-4 The Protein Data BankBox 4-5 Methods: Methods for Determining the Three-Dimensional Structure of ProteinsBox 4-6 Medicine: Death by Misfolding: The Prion DiseasesBox 5-1 Medicine: Carbon Monoxide: A Stealthy KillerBox 6-1 Transformations of Michaelis-Menten Equation: The Double-Reciprocal PlotBox 6-2 Kinetic Tests for Determining Inhibition MechanismsBox 6-3 Evidence for Enzyme-Transition State ComplementarityBox 7-1 Medicine: Blood Glucose Measurements in the Diagnosis and Treatment of DiabetesBox 9-1 A Potent Weapon in Forensic MedicineBox 9-2 Medicine: The Human Genome and Human Gene TherapyBox 10-1 Sperm Whales: Fatheads of the DeepBox 10-2 Medicine: Abnormal Accumulation of Membrane Lipids: Some Inherited Human DiseasesBox 11-1 Methods: Atomic Force Microscopy to Visualize Membrane ProteinsBox 11-2 Medicine: Defective Glucose and Water Transport in Two Forms of DiabetesBox 11-3 Medicine: A Defective Ion Channel in Cystic FibrosisBox 12-1 Methods: Scatchard Analysis Quantifies the Receptor-Ligand InteractionBox 12-2 Medicine: G Proteins: Binary Switches in Health and DiseaseBox 12-3 Methods: FRET: Biochemistry Visualized in a Living CellBox 12-4 Medicine: Color Blindness: John Dalton's Experiment from the GraveBox 12-5 Medicine: Development of Protein Kinase Inhibitors for Cancer TreatmentBox 13-1 Firefly Flashes: Glowing Reports of ATPBox 14-1 Medicine High Rate of Glycolysis in Tumors Suggests Targets for Chemotherapy and Facilitates DiagnosisBox 14-2 Athletes, Alligators and Coelacanths: Glycolysis at Limiting Concentrations of OxygenBox 14-3 Ethanol Fermentations: Brewing Beer and Producing BiofuelsBox 14-4 Medicine: Why Pythagoras Wouldn't Eat Falafel: Glucose-6-Phosphate Dehydrogenase DeficiencyBox 15-1 Methods: Metabolic Control Analysis: Quantitative AspectsBox 15-2 Isozymes: Different Proteins That Catalyze the Same ReactionBox 15-3 Medicine: Genetic Mutations That Lead to Rare Forms of DiabetesBox 15-4 Carl and Gerty Cori: Pioneers in Glycogen Metabolism and DiseaseBox 16-1 Moonlightning Enzymes: Proteins with More Than One JobBox 16-2 Synthases and Synthetases; Ligases and Lyases; Kinases, Phosphatases, and Phosphorylases: Yes, the Names Are Confusing!Box 16-3 Citrate: A Symmetric Molecule That Reacts AsymmetricallyBox 16-4 Citrate Synthase, Soda Pop, and the World Food SupplyBox 17-1 Fat Bears Carry Out beta Oxidation in Their SleepBox 17-2 Coenzyme B12: A Radical Solution to a Perplexing ProblemBox 18-1 Medicine: Assays for Tissue DamageBox 18-2 Medicine: Scientific Sleuths Solve a Murder MysteryBox 19-1 Hot, Stinking Plants and Alternative Respiratory PathwaysBox 21-1 Mixed-Function Oxidases, Oxygenases, and Cytochrome P-450Box 21-2 Medicine: ApoE Alleles Predict Incidence of Alzheimer's DiseasesBox 21-3 Medicine: The Lipid Hypothesis and the Development of StatinsBox 22-1 Unusual Lifestyles of the Obscure but AbundantBox 22-2 Medicine: On Kings and VampiresBox 22-3 Medicine: Curing African Sleeping Sickness with a Biochemical Trojan HorseBox 23-1 Medicine: How Is a Hormone Discovered? The Arduous Path to Purified InsulinBox 24-1 Medicine: Curing Diseases by Inhibiting TopoisomerasesBox 24-2 Medicine: Epigenetics, Nucleosome Structure, and Histone VariantsBox 25-1 Medicine DNA Repair and CancerBox 26-1 Methods: RNA Polymerase Leaves Its Footprint on a PromoterBox 26-2 Medicine: Fighting AIDS with Inhibitors of HIV Reverse TranscriptaseBox 26-3 Methods: The SELEX Method for Generating RNA Polymers with New FunctionsBox 26-4 An Expanding RNA Universe Filled with TUF RNAsBox 27-1 Exceptions That Prove the Rule: Natural Variations in the Genetic CodeBox 27-2 From an RNA World to a Protein WorldBox 27-3 Natural and Unnatural Expansion of the Genetic CodeBox 27-4 Induced Variation in the Genetic Code: Nonsense SuppressionBox 28-1 Of Fins, Wings, Beaks, and Things 内容介绍：他生物化学原理，二十五年前写的阿尔伯特Lehninger的第一版，曾担任出发点和模型我们的四个后续版本。过了四分之一世纪，生物化学的世界已经发生巨大变化。二十五年前，不是一个单一的基因组被测序，而不是一个单一的膜蛋白已经解决了晶体，而不是一个单一的基因敲除小鼠的存在。核酶刚刚被发现的，PCR技术引进和古确认为独立王国细菌的成员。现在，新的基因组序列是每周公布，新的蛋白质结构更加频繁，研究人员设计的数千种不同的基因敲除小鼠，对基本生物化学，生理学和医学的进步带来巨大的希望。第5版中包含的，因为生物化学原则，其中第一版谁收到他们的奖品为化学或生理学或医学31位诺奖获得者的照片。he first edition of Principles of Biochemistry, written by Albert Lehninger twenty-five years ago, has served as the starting point and the model for our four subsequent editions. Over that quarter-century, the world of biochemistry has changed enormously. Twenty-five years ago, not a single genome had been sequenced, not a single membrane protein had been solved by crystallography, and not a single knockout mouse existed. Ribozymes had just been discovered, PCR technology introduced, and archaea recognized as members of a kingdom separate from bacteria. Now, new genomic sequences are announced weekly,new protein structures even more frequently, and researchers have engineered thousands of different knock out mice, with enormous promise for advances in basic biochemistry, physiology, and medicine. This fifth edition contains the photographs of 31 Nobel laureates who have received their prizes for Chemistry or for Physiology or Medicine since that first edition of Principles of Biochemistry.One major challenge of each edition has been to reflect the torrent of new information without making the book overwhelming for students having their first encounter with biochemistry. This has required much careful sifting aimed at emphasizing principles while still conveying the excitement of current research and its promise for the future. The cover of this new edition exemplifies this excitement and promise: in the x-ray structure of RNA polymerase, we see DNA, RNA, and protein in their informational roles, in atomic dimensions, caught in the central act of information transfer.One major challenge of each edition has been to reflect the torrent of new information without making the book overwhelming for students having their first encounter with biochemistry. This has required much care ful sifting aimed at emphasizing principles while still conveying the excitement of current research and it spromise for the future. The cover of this new edition exemplifies this excitement and promise: in the x-ray structure of RNA polymerase, we see DNA, RNA, and proteinin their informational roles, in atomic dimensions, caught in the central act of information transfer.We are at the threshold of a new molecular physiology in which processes such as membrane excitation,secretion, hormone action, vision, gustation, olfaction,respiration, muscle contraction, and cell movements willbe explicable in molecular terms and will become accessible to genetic dissection and pharmacological manipulation. Knowledge of the molecular structures of thehighly organized membrane complexes of oxidative phosphorylation and photophosphorylation, for example, will certainly bring deepened insight into those processes, so central to life. (These developments make us wish we were young again, just beginning our careers in biochemical research and teaching. Our book is not the only thing that has acquired a touch of silver overthe years!)In the past two decades, we have striven always to maintain the qualities that made the original Lehninger text a classic—clear writing, careful explanations of difficult concepts, and communicating to students the ways in which biochemistry is understood and practiced today.We have written together for twenty years and taught together for almost twenty-five. Our thousands of students at the University of Wisconsin–Madison over those years have been an endless source of ideas about how to present biochemistry more clearly; they have enlightened and inspired us. We hope that this twenty-fifth anniversaryedition will enlighten and inspire current students of biochemistry everywhere, and perhaps lead some of them to love biochemistry as we do.内容截图：电子书www.minxue.net资源:[Lehninger.Principles.Of.Biochemistry.Fifth.Edition].David.L.Nelson.扫描版.PDF...

简介:  目录:  About the Authors iiiPreface vAcknowledgmentsDetailed Contents xvA Preview of the CellThe Chemistry of the CellThe Macromolecules of the CellCells and OrganellesBioenergetics: The Flow of Energy in the CellEnzymes: The Catalysts of LifeMembranes: Their Structure, Function,and ChemistryTransport Across Membranes:Overcoming the Permeability BarrierChemotrophic Energy Metabolism:Glycolysis and Fermentation zzChemotrophic Energy Metabolism Aerobic RespirationPhototrophic Energy Metabolism:PhotosynthesisThe Endomembrane System and PeroxisomesSignal Transduction Mechanisms: I. Electrical and Synaptic Signaling in NeuronsSignal Transduction Mechanisms: II. Messengers and ReceptorsCytoskeletal SystemsCellular Movement: Motility and ContractilityBeyond the Cell: Cell Adhesions, Cell Junctions, and Extracellular Structures 480The Structural Basis of Cellular Information: DNA, Chromosomes, and the NucleusThe Cell Cycle, DNA Replication, and MitosisSexual Reproduction, Meiosis, and Genetic Recombination 600Gene Expression: I. The Genetic Code and TranscriptionGene Expression: II. Protein Synthesis and SortingThe Regulation of GeneExpressionCancer CellsAppendix: Visualizing Cells and Molecules GlossaryPhoto, Illustration, and Text CreditsIndex 内容介绍：本书由美国威斯康星大学、密歇根大学4位教授合作编写，在世界上享有盛誉，是细胞生物学学科经典教材之一。本书在亚马逊专业教材销售排行榜长期名列前茅，读者评价较高，并被许多北美、欧洲高校教学选用。本书编写内容全面、理念先进，并具有鲜明的教学使用特色--适当的深度与简明性、艺术化教学、多层次解答问题、力求精准的概念阐述、为提高教学与学习效率而设计的诸多辅助学习内容。第七版主要内容涵盖：生物信息、生物能、代...WAYNE M.BECKER,taught cell biology at the University of Wisconsin Madison,for 30 years until his recent retirement.His interest in textbook writing grew out of notes,outlines,and problem sets that he assembled for his students,culminating in Energy and the Living Cell,a paperback text on bioenergetics pubfished in 1977,and The World of the Cell,the first edition of which appeared in 1986.He earned all his degrees at the University of Wisconsin-Madison.All three degrees are in biochemistry,an orientation that is readily dis-cernible in his textbooks.His research interests have been in plant molecular biology,focused specifically on the regulatinn of theexpression of genes that encode enzymes of the photorespiratorypathway.His interests in teaching,learning,and research have taken him on sabbatical leaves at Harvard University,Edinburgh University,the University of Indonesia,the University of Puerto Rico,Canterbury University in Christchurch,New Zealand,the Chinese University of Hong Kong,and the Charles University in Prague.His honors include a Chancellor's Award for Distin-gnished Teaching,Guggenheim and Pulbright Fellowships,and a Visiting Scholar Award from the Royal Society of London. LEWIS J.KLEINSMITH is an Arthur F.Thurnau Professor Emeritus of Molecular,Cellular,and Developmental biology at the University of Michigan,where he has served on the faculty since receiving his Ph.D.from Rockefeller University in 1968.His teaching experiences have involved courses in introductory biology,cell biology,and cancer biology,and his research interests have included studies of growth control in cancer cells,the role of protein phosphorylation in eukaryotic gene regulation,and the control of gene expression during development.Amonghis numerous publications,he is the author of Principles of Cancer Biology as well as several award winning educational software programs.His honors include a Guggenheim Feblowship,the Henry Russell Award,a Michigan Distinguished Service Award,citations for outstanding teaching from the Michigan Students Association,an NIH Plain Language Award,and a Best Curriculum innovafion Award from the EDUCOM Higher Education Software Awards Competition. JEFF HARDIN is a Professor in the Zoology Department at the University of Wisconsln-Madlson.His research interests center on how cells migrate and adhere to one another to change the shape of ainmal embryos.Dr.Hardin's teaching is enhanced by his extensive use of videomicroscopy and his Web based teaching materials,which areused on many campuses in the United States and other countries.As part of his interest in teaching biology,Dr.Hardin has been involved in several teaching initiatives.He was a founding member of the University of Wisconsin Teaching Academy and a cofounder of a Univer-sity of Wisconsin system wide instructional technology initiative known as BioWeh.He is currently thcudy directorof the Biology Core Curriculum,a four-semester honors biology sequence for undergraduates.His teaching award sinclude a Lily Teaching Fellowship and a National Science Foundation Young Investigator Award.He is also on theeditorial board of CBE: Life Sciences Education. GREGORY PAUL BERTONI,the newest member of the author team,has been active in teaching and research for over 20 years.He earned a Ph.D.in Cellular and Molecular Biology from the University of Wisconsin Madison,where his teaching experiences included introductory and graduate level biochemistry,sophomore cell biology,and plant physiology.He also helped to develop a new course entitled "Ways of Knowing" designed to introduce entering,freshmen to the learning process itself.His puhdshed research includes studies in bacterial pathogenesis,plant-microbe interactions,and plant gene expression.He is currently teaching biology and medical microbiology at Columbus State Community College in Columbus,Ohio,where he has just been nominated for a Distinguished Teaching Award.In addition,Dr.Bertoni is a freelance scientific writer who has contributed to text- and web based projects in biology,physics,and microbiology.He is also a science editor for The Plant Cell,a leading research journal in plant biology and molecular biology.内容截图：电子书www.minxue.net资源:[The.World.Of.The.Cell].Wayne.M.Becker等著.扫描版.PDF如需下载资源，发送邮件VeryCDdisk1@outlook.com ...

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又名系统仿真与模拟,共计24讲 陆续继续更新简介：第1章 系统仿真技术与应用第2章 matlab语言程序设计基础第3章 matlab语言在现在科学运算中的应用第4章 matlab/simulink下数学模型建立与仿真系统仿真课程总复习此相关专业课程：概率论与数理统计电子技术基础机械原理机械设计程序设计　微机原理与应用机电控制技术　网络与数据通信机械工程应用软件系统仿真与模拟机械工程测试技术数控加工技术机械工程前沿专题讲座Windows程序设计（VB.NET）控制理论基础机器人技术数据库应用基础嵌入式系统及应用毕业设计　 ...

简介:  目录:  专家推荐序 姜奇平 段永朝第1章 我的疑惑第2章 发明我们自己第3章 第七王国的历史第4章 外熵的扩展第5章 大发展第6章 注定的发展方向第7章 趋同性第8章 倾听科技之声第9章 选择必然第10章 邮包炸弹客言之有理第11章 阿米什改装者的经验第12章 寻找欢乐第13章 科技的轨迹第14章 无限博弈 内容介绍：凯文·凯利向我们介绍了一种全新的科技观。他认为，作为整体，科技不是由线路和金属构成的一团乱麻，而是有生命力的自然形成的系统，它的起源完全可以回溯到生命的初始时期。正如生物进化呈现出无意识的趋势，科技也是如此。通过追踪这些长期趋势，我们可以对“科技想要什么”有所理解。在《科技想要什么》一书中，凯文·凯利预测了未来数十年科技的12种趋势，包括创造大脑这一得寸进尺之举。不过，为了让人类创造的世界实现收益最大化，需要对这种全球体系产生的问题和代价保持敏感。凯利详细讲述了值得我们学习的阿米什“早期使用者”和其他批判科技自我主义倾向的人所具有的智慧。凯利的新科技理论提供了三种实践经验：通过倾听科技的需求，我们和我们的孩子可以更加出色地做好准备，迎接必将到来的科技；通过采用主动融合原则，我们可以驾驭科技，使之发挥最大作用；通过遵从这种类生命系统的长期规则，我们可以获得它的全部馈赠。凯利令人吃惊地宣称，现在人类已定义的生命形态仅包括植物、动物、原生生物、真菌、原细菌、真细菌六种，但技术的演化和这六种生命体的演化惊人相似。技术应该是生命的第七种存在方式。技术是生命的延伸，它不是独立于生命之外的东西 。作者简介：1952年，凯文·凯利出生于美国东北部宾夕法尼亚州。19岁，他从罗得岛大学退学。接下来，他做了8年左右的独立摄影师，去过亚洲十几个国家。1979年，27岁的时候，凯利去中东的耶路撒冷，在哪里成为基督徒。之后，他骑自行车穿越美国大陆。然后，《连线》开始进入KK生命，并以一种预告未来的方式切入时代脉搏。凯文·凯利参与创建《连线》杂志，在前7年里担任执行主编。他在《纽约时报》、《经济学人》、《科学》、《时代》和《华尔街日报》以及其他许多出版物上发表文章。已出版著作包括畅销书《失控》和《新经济的新规则》。内容截图： ...